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CORRESP

Gritstone Oncology, Inc.

5858 Horton Street, Suite 210

Emeryville, California 94608

September 25, 2018

VIA EDGAR AND E-MAIL

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549-6010

 

Attention:

Mary Beth Breslin

    

Ada D. Sarmento

    

Jim B. Rosenberg

    

Rolf Sundwall

 

  Re:

Gritstone Oncology, Inc. Registration Statement on Form S-1 (Registration No. 333-226976)

Ladies and Gentlemen:

In accordance with Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-1 (File No. 333-226976) (the “Registration Statement”) of Gritstone Oncology, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:00 p.m., Washington, D.C. time, on September 27, 2018, or as soon as practicable thereafter. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Latham & Watkins LLP, by calling Brian Cuneo at (650) 463-3014.

Thank you for your assistance in this matter.

 

Very truly yours,

GRITSTONE ONCOLOGY, INC.

By:

 

 

/s/ Andrew Allen

 

 

Andrew Allen, M.D., Ph.D.

 

President and Chief Executive Officer

 

CC:

Jean-Marc Bellemin, Gritstone Oncology, Inc.

    

Alan C. Mendelson, Latham & Watkins LLP

    

Brian J. Cuneo, Latham & Watkins LLP

    

David Peinsipp, Cooley LLP