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CORRESP

Gritstone bio, Inc.

5959 Horton Street, Suite 300

Emeryville, California 94608

October 27, 2021

VIA EDGAR TRANSMISSION

Securities and Exchange Commission

Division of Corporation Finance

Mail Stop 3010

100 F Street, N.E.

Washington, D.C. 20549

 

  Re:

Gritstone bio, Inc.

 

      

Registration Statement on Form S-3 (Registration No. 333-260292)

To the addressees set forth above:

In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-3 (Registration No. 333- 260292) (the “Registration Statement”) of Gritstone bio, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:00 p.m., Eastern Time, on October 29, 2021, or at such later time as the Company or its counsel may orally request via telephone call to the staff. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Latham & Watkins LLP, by calling Brian Cuneo at (650) 463-3014 or Nimrah Khan at (415) 395-8199.

If you have any questions regarding the foregoing, please do not hesitate to contact Brian Cuneo at (650) 463-3014 or Nimrah Khan at (415) 395-8199, of Latham & Watkins LLP. Thank you in advance for your consideration.

 

Sincerely,

 

GRITSTONE BIO, INC.

By:   /s/ Rahsaan Thompson
  Name:  Rahsaan Thompson
  Title:    Executive Vice President and General Counsel

 

cc:

Brian Cuneo, Latham & Watkins LLP

Nimrah Khan, Latham & Watkins LLP